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About LSSL Technology
Avanti Nano’s Life Sciences @ Speed of
Light (LSSL) technology is built on proven, time tested
technology —fluorescent compounds, acousto-optics,
nanocomposites, digital signal processing and traditional
biochemistry — that have been integrated in a unique way.
Featuring a flexible, open-architecture design, LSSL
technology can be configured to perform a wide variety of
life science based applications quickly, cost-effectively
and accurately.
Open-architecture LSSL technology,
developed by Avanti NanoSciences, is ideally suited to a
wide range of applications throughout the drug-discovery
development, manufacturing process monitoring, molecular
diagnostics, bio defense, clinical end point monitoring and
food safety as well as basic Life Science research. Highly
sensitive and accurate, yet designed for high throughput and
increased assay speed, LSSL technology can help clinicians
and researchers alike save time and costs while boosting
productivity.
First, we color-code brightly
fluorescent nanoparticles, called NanoBindisTM,
into number of distinct probe-specific sets. Each set can be
coated with a reagent specific to a particular biomarker,
allowing the capture and detection of specific analytes from
a sample. Within the Gate Keeper ID compact analyzer, light
sources excite the internal dyes within the silica shell
that identify each nano particle. Multiple readings are made
on each set, further validating the results. By
incorporating different fluorescent dyes within the silica
shell, LSSL technology allows multiplexing as well as multi
parameter testing of number of unique assays within a single
sample, both rapidly and precisely.
Technology Advantages and
Benefits:
- Reduced cost and labor
by multiplexing and multi-parameter testing
- Shortened time-to-results by
favorable reaction kinetics of silica shell with
fluorescent core array approach, with smaller sample
requirements
- Multi parameter testing ensures
increased sensitivity and reliability as compared to
traditional single parameter testing for individual
biomarker.
- Incorporation of different
fluorescent dyes within the silica shell allows
multiplexing in single test medium. Focused, flexible
multiplexing and multi parameter testing meets the needs
of a wide variety of applications - protein or gene
expression profiling, clinical biomarker monitoring for
drug efficacy, product validation, microbial detection,
bio defense, drug discovery and development and a
variety of commercial applications.
- Open architecture platform allows
market leading companies to provide compatible kits and
software
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